Antibiotic Resistance Mechanisms Focusing on Quinolones Resistance in Vibrio CHOLERAE
نویسندگان
چکیده
منابع مشابه
Antibiotic resistance mechanisms of Vibrio cholerae.
As the causative agent of cholera, the bacterium Vibrio cholerae represents an enormous public health burden, especially in developing countries around the world. Cholera is a self-limiting illness; however, antibiotics are commonly administered as part of the treatment regimen. Here we review the initial identification and subsequent evolution of antibiotic-resistant strains of V. cholerae. An...
متن کاملMultidrug resistance in Vibrio cholerae.
Cholera continues to be endemic in a large geographical tract covering a number of states in the eastern, western and southern parts of India. Even though V. cholerae non-01 has been reported from some parts of Delhi(l), V. cholerae-01 biotype Eltor continues to be the main etiological agent identified from Delhi(2). Rapid replacement of fluid and electrolyte using oral rehydration therapy or i...
متن کاملantibiotic resistance of vibrio cholerae isolates from kashan, iran
aims: cholera is an acute diarrheal disease that can lead to severe dehydration and death. antibiotic resistance is a big challenge in infective disease like cholera. the present study aimed to understand the characteristics and trends of antibiotic resistance of v. cholerae isolations in and around kashan, iran. instrument & methods: in this descriptive cross-sectional study, samples were gath...
متن کاملMechanisms of resistance to quinolones.
The increased use of fluoroquinolones has led to increasing resistance to these antimicrobials, with rates of resistance that vary by both organism and geographic region. Resistance to fluoroquinolones typically arises as a result of alterations in the target enzymes (DNA gyrase and topoisomerase IV) and of changes in drug entry and efflux. Mutations are selected first in the more susceptible t...
متن کاملTransferable quinolone resistance in Vibrio cholerae.
Ciprofloxacin was introduced for treatment of patients with cholera in Bangladesh because of resistance to other agents, but its utility has been compromised by the decreasing ciprofloxacin susceptibility of Vibrio cholerae over time. We correlated levels of susceptibility and temporal patterns with the occurrence of mutation in gyrA, which encodes a subunit of DNA gyrase, followed by mutation ...
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ژورنال
عنوان ژورنال: International Journal of Infection
سال: 2016
ISSN: 2383-1413,2383-1421
DOI: 10.5812/iji.40622